Isabella of Aragon ¹⁶⁹⁶

   Cause of her death was Childbirth.¹⁶⁹⁵

Isabella married Afonso Prince of Portugal. (Afonso Prince of Portugal was born on 18 May 1475 in Lisbon, Lisboa, Portugal ¹⁶⁹⁶ and died on 13 Jul 1491 ¹⁶⁹⁶.). The cause of his death was Horse riding accident in the margins of the Tagus river..¹⁶⁹⁵

Isabella next married Manuel I "the Fortunate" King of Portugal in 1497.¹⁶⁹⁶ (Manuel I "the Fortunate" King of Portugal was born on 31 May 1469 in Alcochete, Setúbal, Portugal and died on 13 Dec 1521 in Lisbon, Lisboa, Portugal ¹⁶⁹⁶.). The cause of his death was Plague.¹⁶⁹⁵